After a chaotic opening weekend, the NFL moves into Week 2 with injuries once again dominating the headlines. Week 1 produced several significant setbacks: Kyler Murray’s Vikings debut ended early with a first-quarter concussion, Chargers receiver Ladd McConkey was hurt in L.A.’s upset loss to the Cardinals, and Sam Darnold suffered a soft-tissue injury that forced him out of the opener and will keep him sidelined into Week 2. Also notable from opening weekend, A.J. Brown (ankle), Landon Dickerson (knee) and Myles Garrett (knee) all landed on injured reserve. With most teams taking the practice field Wednesday, here are the first injury updates, plus the final reports and statuses for Thursday night’s Lions-Bills game.
Detroit Lions vs. Buffalo Bills (Thursday, 8:15 p.m., Amazon)
– Lions: OG Christian Mahogany (hip) and RT Blake Miller (knee) are officially out. CB D.J. Reed (foot) is questionable after being limited Wednesday.
– Bills: S Cole Bishop (knee/groin), RB Ty Johnson (hamstring) and DL T.J. Sanders (knee/illness) are all listed as questionable after limited practice Wednesday.
The Lions’ report is especially concerning given the loss of both starting offensive linemen, while Buffalo has three players whose availability is uncertain.
Carolina Panthers at Atlanta Falcons (Sunday, 1 p.m., Fox/Fubo)
– Panthers: Edge rusher Patrick Jones II (back) remained sidelined Wednesday, as did DT Bobby Brown III. WR Jalen Coker, who had a huge game in Week 1, was limited with an ankle and has been seen in a walking boot but hopes to play Sunday.
– Falcons: QB Tua Tagovailoa (oblique), CB A.J. Terrell (shoulder) and G Chris Lindstrom (concussion) did not practice Wednesday. QBs Cooper Rush (back) and Michael Penix Jr. (knee) were full participants, with Penix’s availability for Sunday a question.
Minnesota Vikings at Chicago Bears (Sunday, 1 p.m., Fox/Fubo)
– Vikings: WR Jauan Jennings missed Wednesday for personal reasons. LB Blake Cashman (wrist), QB Kyler Murray (concussion), OT Brian O’Neill (knee) and OLB Andrew Van Ginkel (chest) were limited.
– Bears: DT Neville Gallimore (illness) and OT Darnell Wright (knee) did not practice. RB Kyle Monangai (hamstring), CB Malik Muhammad (ankle), DE Dayo Odeyingbo (shoulder), RB D’Andre Swift (ankle/knee), OT Ozzy Trapilo (knee) and S Xavier Woods (groin) were limited.
Philadelphia Eagles at Tennessee Titans (Sunday, 1 p.m., Fox/Fubo)
– Eagles: DT Jalen Carter (wrist) and DB Cooper DeJean (calf/abdomen) missed Wednesday’s practice; Jonathan Greenard was limited (pectoral).
– Titans: LB Cedric Gray has cleared concussion protocol and was a full participant after missing Week 1; LB James Williams was limited with an elbow issue.
Pittsburgh Steelers at New England Patriots
– Steelers: OT Troy Fautanu (ankle) and TE Darnell Washington (personal) missed practice. WR Michael Pittman Jr. (foot) and CB Joey Porter Jr. were limited; Pittsburgh labeled Porter’s absence as conditioning-related, though he missed last Sunday’s game with a back issue.
– Patriots: OT Dametrious Crownover (knee) and CB Carlton Davis III (neck) did not practice. C Ben Brown (knee), DE Dre’Mont Jones (foot) and LB Robert Spillane (knee) were limited.
Green Bay Packers at New York Jets (Sunday, 1 p.m., Fox/Fubo)
– Packers: DT Warren Brinson missed practice with a calf issue. OL Zach Bako-Bewele (knee), G Aaron Banks (knee), DT Javon Hargrave (knee/concussion), LB Ty’Ron Hopper (Achilles), EDGE Barryn Sorrell (foot), EDGE Lukas Van Ness (concussion) and DT Devonte Wyatt (ankle) were limited.
– Jets: Rookie WR Omar Cooper Jr. (ankle), S Minkah Fitzpatrick (groin), RB Kene Nwangwu (back) and EDGE Joseph Ossai (foot) did not practice. CB D’Angelo Ponds (calf) and LB Jamien Sherwood (knee) were limited.
Cleveland Browns at Tampa Bay Buccaneers
– Browns: OL Teven Jenkins remains out with a back injury. C Parker Brailsford (thumb), DT Maliek Collins (quad), OL Elgton Jenkins (back) and OT Dawand Jones (head) were limited Wednesday.
– Buccaneers: S Miles Killebrew (concussion) and CB Jacob Parrish (back) were limited in practice. WR Jalen McMillan (knee) and RB Sean Tucker (hamstring) were full participants.
New Orleans Saints at Baltimore Ravens
– Saints: TE Juwan Johnson (illness) and LB Isaiah Stalbird (shoulder) missed practice. DE Cameron Jordan and rookie TE Oscar Delp were limited with hamstring issues.
– Ravens: Several players sat out Wednesday — WR Zay Flowers (hamstring), EDGE Trey Hendrickson (finger), G John Simpson (groin), OT Ronnie Stanley (toe) and CB T.J. Tampa (knee) — while LB Teddye Buchanan (knee), S Keondre Jackson (shoulder) and DT Nnamdi Madubuike (neck) were limited.
Cincinnati Bengals at Houston Texans
– Bengals: QB Joe Burrow was limited in practice with a back issue but told reporters he plans to play Sunday. EDGE Shemar Stewart was a full participant despite a knee concern.
– Texans: EDGE Jadeveon Clowney (knee) and LB Jake Hummel (groin) did not practice; WR Nico Collins was limited with a hamstring issue.
Jacksonville Jaguars at Denver Broncos
– Jaguars: RB LeQuint Allen Jr. (hip), WR Jakobi Meyers (thumb), LB Foye Oluokun (wrist), WR Brian Thomas Jr. (shoulder) and G Cole Van Lanen (knee) were limited in practice.
– Broncos: RB R.J. Harvey (hamstring) and WR Marvin Mims Jr. (foot) missed Wednesday’s session.
Las Vegas Raiders at Los Angeles Chargers
– Raiders: TE Brock Bowers (knee) and CB Darien Porter (foot) missed practice. RB Ashton Jeanty was listed with an ankle issue but practiced fully.
– Chargers: WR Ladd McConkey (rib), CB Elijah Molden (hamstring), OT Trey Pipkins (knee) and DT Teair Tart (ankle) did not practice. CB Deane Leonard (abdomen) and DE Dalvin Tomlinson (hamstring) were limited.
Washington Commanders at Dallas Cowboys (Sunday, 4:25 p.m., Fox/Fubo)
– Commanders: LB Frankie Luvu (groin) and TE Chig Okonkwo (hamstring) missed practice. Pass rushers Dorance Armstrong (knee), K’Lavon Chaisson (knee), Charles Omenihu (ankle) and Odafe Oweh (calf) were limited; DT Daron Payne (knee) and WR Jaylin Lane (groin) were also limited.
– Cowboys: S Malik Hooker (forearm) and LB DeMarvion Overshown (hamstring) did not practice. EDGE James Houston was limited with a shoulder issue.
Seattle Seahawks at Arizona Cardinals (Sunday, 4:25 p.m., Fox/Fubo)
– Seahawks: QB Sam Darnold (glute) remains out of practice and is expected to miss roughly four weeks but will not be placed on IR. S Ty Okada (hamstring) also sat out. OG Anthony Bradford (knee), S Nick Emmanwori (ankle/hip), OT Josh Jones (knee) and WR Cooper Kupp (back) were limited.
– Cardinals: OL Isaac Seumalo missed practice with a shoulder issue. Isaiah Adams (knee), LB Jack Gibbens (shoulder), DL Roy Lopez (groin), CB Max Melton (ankle), LB Cody Simon (shoulder), S Dadrion Taylor-Demerson (ribs) and CB Garrett Williams (Achilles) were limited. Rookie RB Jeremiyah Love was not on the report (good news for Arizona).
Miami Dolphins at San Francisco 49ers (Sunday, 4:25 p.m., Fox/Fubo)
– Dolphins: LB Ronnie Harrison (hamstring) missed practice. EDGE Chop Robinson (concussion) and TE Seydou Traore (thumb/Achilles) were limited. QB Malik Willis had a toe issue listed but practiced fully.
– 49ers: K Eddy Pineiro missed practice due to illness. DL Keion White (back), TE George Kittle (Achilles), DL Khalid Kareem (shoulder) and FB Kyle Juszczyk (finger) were limited.
Indianapolis Colts at Kansas City Chiefs (Sunday, 8:20 p.m., NBC/Fubo)
– Colts: WR Ashton Dulin (ankle) and QB Anthony Richardson (groin) did not practice Wednesday. LB Austin Ajiake was limited with a hamstring concern.
– Chiefs: DB Chamarri Conner (knee) and OT Josh Simmons (back) missed practice; DT Chris Jones was limited with a calf issue.
Fan Take: Injuries are already reshaping Week 2 storylines and could have ripple effects across team game plans and depth charts — especially when starting linemen, quarterbacks or key defensive playmakers are limited or ruled out. For fans, these early-season health concerns make monitoring practice reports essential, because unexpected absences can swing matchups, fantasy lineups and the momentum of the entire season.
Source: www.cbssports.com
