Plenty of injuries are shaping this weekend’s NFL slate. Below is a rewritten summary of each team’s final report and the latest updates heading into Week 3.
Quick notes before the team-by-team lists: Seahawks QB Sam Darnold is expected to return after missing time with a glute injury sustained in Week 1. Rams star WR Puka Nacua (hip/groin) is doubtful for Sunday night in Denver. 49ers pass rusher Nick Bosa pulled a calf in practice and is expected to miss several weeks, and Jaguars QB Jaxson Dart had season-ending knee surgery on Friday with an estimated 4–6 month recovery.
Sunday, Sept. 27
Chargers at Bills
– Chargers: Kayode Awosika (G, fibula), Charlie Kolar (TE, forearm), Elijah Molden (DB, hamstring), Trey Pipkins III (G/T), Brenen Thompson (WR, quad), Dalvin Tomlinson (DL, hamstring) — OUT. Trey Lance (QB, groin) and Rodney Shelley (CB, hamstring) — QUESTIONABLE.
– If Lance can’t go, the Chargers could promote DJ Uiagalelei from the practice squad. Jim Harbaugh said Trevor Penning will start left guard for Awosika.
– Bills: Jordan Hancock (DB, hamstring), T.J. Sanders (DL, illness) — OUT. Keon Coleman (WR, ankle), DJ Moore (WR, shoulder), Ed Oliver (DL, hip), Ar’maj Reed-Adams (G, elbow) — QUESTIONABLE.
– Coach Joe Brady called Coleman and Moore game-time decisions after limited practice Friday.
Panthers at Browns
– Panthers: Devin Lloyd (LB, calf), Claudin Cherelus (LB, shoulder), Nick Scott (S, rib) — OUT. Jalen Coker (WR, ankle), Xavier Legette (WR, knee) — QUESTIONABLE.
– Lloyd, last week’s NFC Defensive Player of the Week, didn’t practice all week. Coach Dave Canales expects Coker to play; Legette is a game-time decision.
– Browns: Teven Jenkins (OL, back) — OUT. Tyson Campbell (CB, ankle/hip/knee), Grant Delpit (S, shoulder) — QUESTIONABLE.
– Campbell and Delpit were limited in practice and could play; Jenkins will miss his third straight game.
Jets at Lions
– Jets: Minkah Fitzpatrick (S, groin), Kiko Mauigoa (LB, quad), Mason Taylor (TE, thumb) — OUT. Kene Nwangwu (RB, back) — DOUBTFUL. Adonai Mitchell (WR, finger), Joseph Ossai (EDGE, foot) — QUESTIONABLE.
– Ossai practiced fully Friday; Mitchell was limited Thursday and Friday.
– Lions: Ben Bartch (G, foot), Thomas Harper (S, ankle) — OUT.
– Avonte Maddox suffered a season-ending injury; Christian Izien, Jalen Mills and Bishop Fitzgerald will step up in the secondary.
Texans at Colts
– Texans: Nico Collins (WR, hamstring), M.J. Stewart (DB, knee), Jake Hummel (LB, groin), Ed Ingram (G, groin), Jadeveon Clowney (EDGE, knee) — OUT. Trent Brown (OT, knee/wrist) — QUESTIONABLE.
– Collins’ absence was costly last week; Ingram out and Brown questionable further stress the line, though Brown practiced fully Friday.
– Colts: Ashton Dulin (WR, ankle), Alec Pierce (WR, heel) — OUT. Charvarius Ward Sr. (CB, groin) — QUESTIONABLE.
– Pierce is out after leaving last week’s game early. Ward was a full participant Friday and is trending up.
Patriots at Jaguars
– Patriots: Quintayvious Hutchins (LB, knee), Dre’Mont Jones (LB, shoulder) — OUT. Eli Raridon (TE, thigh), Craig Woodson (S, shoulder) — QUESTIONABLE.
– Raridon missed the last two days of practice; Woodson was limited Friday.
– Jaguars: Albert Regis (DT, elbow) — DOUBTFUL.
Chiefs at Dolphins
– Chiefs: Josh Simmons (T, back) — OUT. Chamarri Conner (DB, knee) — DOUBTFUL.
– Conner was limited in practice each day.
– Dolphins: Rob Beal Jr. (EDGE, hamstring), Caleb Douglas (WR, ankle) — OUT. Jaylen Wright (RB, stinger/foot) — DOUBTFUL. JuJu Brents (CB, knee), Ryan Miller (WR, hip/back) — QUESTIONABLE.
– Brents and Miller were full participants Friday.
Titans at Giants
– Titans: Cor’Dale Flott (CB, quad), Tyjae Spears (RB, ankle) — QUESTIONABLE.
– Flott was questionable all week; Spears was limited Friday but could play. Tony Pollard (RB, ankle) is expected to play after limited practices.
– Giants: Brian Burns (OLB, ankle), Deonte Banks (CB, calf), Tyler Nubin (S, calf) — QUESTIONABLE.
– Burns did not practice all week; Banks and Nubin were limited in practice.
Bengals at Steelers
– Bengals: Andrei Iosivas (WR, thumb) — OUT. B.J. Hill (DT, Achilles) — DOUBTFUL.
– Hill’s possible absence would reduce interior defensive depth. Iosivas’ status could redirect targets to RB Chase Brown, Samaje Perine and TE Mike Gesicki.
– Steelers: Gennings Dunker (G, knee), Rico Dowdle (RB, toe) — OUT. Michael Pittman Jr. (WR, foot), Joey Porter Jr. (CB, NIR/conditioning), Jaylen Warren (RB, shoulder), Jamel Dean (CB, ankle) — QUESTIONABLE.
– Porter was removed from the “back” ailment label this week; if Warren can’t play, with Dowdle already out, Travis Homer would be a likely practice-squad promotion.
Seahawks at Commanders
– Seahawks: Julian Love (S, calf), Ty Okada (S, hamstring) — OUT. Brandon Pili (DT) — QUESTIONABLE.
– AJ Finley will start in Love’s place. Rookie RB Jadarian Price, who left the previous game with a chest issue, practiced fully Friday.
– Commanders: Sam Cosmi (G, concussion/throat), Nick Cross (S, illness), Jayden Daniels (QB, left elbow), Frankie Luvu (LB, groin), Chig Okonkwo (TE, hamstring) — OUT.
– Jayden Daniels is out; Marcus Mariota will start and has performed well since joining Washington, with 15 TDs, seven INTs and a 64.1% completion rate in D.C.
Cardinals at 49ers
– Cardinals: Dadrion Taylor (S, back) — OUT. Roy Lopez (DL, groin), Max Melton (CB, toe) — QUESTIONABLE.
– Both Lopez and Melton were limited Friday after not practicing Thursday.
– 49ers: James Thompson (ankle), DeMarcus Robinson (WR, ankle), Romello Height (DL, hand), Nick Bosa (EDGE, calf) — OUT. Mike Evans (WR, hip) — QUESTIONABLE.
– Bosa’s calf issue could lead to discussions about injured reserve; coach Kyle Shanahan said he doesn’t think the absence will be long-term.
Vikings at Buccaneers
– Vikings: Nick Samac (C, knee), Brett Thorson (P, hamstring) — OUT.
– Samac hasn’t played this season; Johnny Hekker will handle punts after Thorson’s injury. Aaron Jones (knee) practiced fully Friday after limited work earlier in the week.
– Buccaneers: Rueben Bain Jr. (OLB, groin), Josiah Trotter (LB, shoulder) — OUT.
– Al-Quadin Muhammad and SirVocea Dennis are expected to step into the starting roles.
Raiders at Saints
– Raiders: Treydan Stukes (S, concussion) — OUT. Brock Bowers (TE, knee), Aidan O’Connell (QB, personal) — QUESTIONABLE.
– Bowers’ limited practices earlier in the week were part of a planned approach; he didn’t practice Friday.
– Saints: Barion Brown (WR, hamstring), Christen Miller (DL, toe) — OUT. Martin Emerson Jr. (CB, shoulder) — (limited).
– New Orleans is missing recent draft picks: WR Jordyn Tyson (hamstring) is on IR, Miller is out again, and Brown is out. Emerson practiced in a limited capacity Friday.
Ravens vs. Cowboys
– Ravens: Ronnie Stanley (T, toe) — OUT. Zay Flowers (WR, hamstring) — QUESTIONABLE.
– Carson Vinson (2025 fifth-round pick) is slated to start at tackle in place of Stanley. Final Cowboys statuses were not listed.
Rams at Broncos
– Rams: Puka Nacua (WR, hip) and Kamren Kinchens (S, hamstring) — DOUBTFUL. Colby Parkinson (TE, knee) — QUESTIONABLE.
– Nacua missed all practices this week. The Rams still put up 28 points without him last week, with Davante Adams having a big game.
– Broncos: Jonah Coleman (RB, ankle) — OUT. Marvin Mims Jr. (WR, foot) — QUESTIONABLE.
– Coleman didn’t practice all week and will be inactive. J.K. Dobbins (hip) and RJ Harvey (hamstring) practiced fully and are expected to play.
Monday, Sept. 28
Eagles at Bears
– Eagles: Statuses to be announced.
– Bears: Caleb Williams (QB, hamstring), Tyson Bagent (QB, concussion), Joe Thuney (OL, rest), Cairo Santos (K, hip) — DNP. Noah Sewell (LB), Tyrique Stevenson (DB, hamstring), Shemar Turner (DL, knee) — limited. Grady Jarrett and Kyle Monangai (RB, knee) — full.
– Williams’ hamstring injury clouds Chicago’s QB situation; Bagent remains in concussion protocol, so Case Keenum could start. Final designations will be released Saturday.
Fan Take:
Injuries to key players like Puka Nacua and Nick Bosa — plus several teams missing starters across multiple positions — could significantly alter matchups and outcomes this weekend, making depth and roster decisions crucial. For fans, this underscores how quickly a team’s fortunes can shift and why midseason roster management and younger players’ readiness matter more than ever for the league’s competitive balance.
Source: www.cbssports.com

