The Los Angeles Rams opened the 2026 season as overwhelming Super Bowl favorites at +500, but after a 27-7 defeat to the San Francisco 49ers in Australia their chances have weakened. That 20-point loss is the largest Week 1 defeat ever suffered by a preseason Super Bowl favorite in the 50 seasons of available odds data.
Over the last 30 years, teams listed as preseason favorites at +500 or shorter have appeared 20 times — and none of those squads went on to win the Super Bowl.
Below are the DraftKings Super Bowl LXI odds as of Sept. 14:
Rams: +650 (bet $10 to win $75 total)
Ravens: +900 (bet $10 to win $100 total)
Bills: +950 (bet $10 to win $105 total)
Seahawks: +1100 (bet $10 to win $120 total)
49ers: +1400 (bet $10 to win $150 total)
Chiefs: +1600 (bet $10 to win $170 total)
Eagles: +1700 (bet $10 to win $180 total)
Lions: +1800 (bet $10 to win $190 total)
Bengals: +1900 (bet $10 to win $200 total)
Texans: +1900 (bet $10 to win $200 total)
Patriots: +1900 (bet $10 to win $200 total)
Broncos: +1900 (bet $10 to win $200 total)
Chargers: +2000 (bet $10 to win $210 total)
Packers: +2000 (bet $10 to win $210 total)
Bears: +2200 (bet $10 to win $230 total)
Cowboys: +2500 (bet $10 to win $260 total)
Jaguars: +2500 (bet $10 to win $260 total)
Vikings: +4500 (bet $10 to win $460 total)
Steelers: +5000 (bet $10 to win $510 total)
Giants: +5000 (bet $10 to win $510 total)
Buccaneers: +5500 (bet $10 to win $560 total)
Colts: +6500 (bet $10 to win $660 total)
Commanders: +6500 (bet $10 to win $660 total)
Saints: +9000 (bet $10 to win $1,310 total)
Panthers: +9000 (bet $10 to win $910 total)
Falcons: +13000 (bet $10 to win $1,010 total)
Raiders: +15000 (bet $10 to win $1,510 total)
Titans: +20000 (bet $10 to win $2,010 total)
Jets: +25000 (bet $10 to win $2,510 total)
Cardinals: +30000 (bet $10 to win $3,010 total)
Browns: +30000 (bet $10 to win $3,010 total)
Dolphins: +50000 (bet $10 to win $5,010 total)
What to know about the Super Bowl LXI board:
– Trouble in L.A.?: The Rams’ Week 1 blowout loss isn’t their only concern — the report highlights a knee issue sidelining a key defensive player who will require arthroscopic surgery and miss at least four games on injured reserve. Add to that Aaron Donald’s absence from Week 1 while he eases back into playing shape after a two-year break, and the Rams’ vaunted defensive line looks far from the finished product many expected.
– Ravens Rise: Lamar Jackson looked far healthier and sharper than last season, completing 17 of 25 passes for 324 yards and a touchdown while adding 40 rushing yards and a score on seven carries. Zay Flowers finished with five catches for 150 yards and a TD, and Derrick Henry ran for 144 yards and three touchdowns on 24 carries as the Ravens beat the Colts 41-23 on the road — a performance that nudged Baltimore from +1000 to +900, just ahead of Buffalo at +950.
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Fan Take: This shift matters because early losses and injury news can rapidly reshape betting markets and public perception — favorites aren’t immune to quick downgrades. For fans, it’s a reminder that preseason labels mean little once the games begin, and the real storylines often come from unexpected starts and early health developments.
Source: www.foxsports.com
